Run for ALD, Cure the Boys

• Date: Saturday, November 21st, 2026
• Time: 9:00 AM
• In-person location: Creve Coeur Park (near St. Louis, MO)
• Virtual option: Participate from wherever you are, on your own schedule

Teams are an important part of our mission and key to raising awareness and funds. During registration, you can create or join a team to rally your friends, family, and coworkers.

Adrenoleukodystrophy (ALD) is a progressive, rare genetic disease that affects about 1 in 15,000 people worldwide. It progressively damages the adrenal glands, spinal cord, and myelin of the nervous system. It most severely affects boys, some of whom suffer severe neurological symptoms that can result in death if the disease is undiagnosed and not treated very early.

Our why: This event is inspired by the vision of our son, Nicholas, who underwent a successful bone marrow transplant to halt the progression of his cerebral ALD at the University of Minnesota Children's Hospital (a world leader in ALD treatment).

100% of the funds raised from this event go directly to the University of Minnesota Leukodystrophy Center for ALD Research. Your support funds early identification, more effective therapies, treatment options, and hopefully, one day, a cure.

The majority of our impact comes from donations above and beyond race registrations. If you cannot participate, or want to make an even bigger difference, you can support us in these ways:

1. Add a donation during registration.
2. Direct donation: Use the "Donate" tab on this page to give without registering.
3. Donate by check to avoid online processing fees. Mail it to: Knockout ALD, 1551 Timberlake Manor Parkway, Chesterfield, MO 63017.

A free event T-shirt is included with both in-person and virtual registrations.

T-shirt deadline: Register by October 21st to guarantee your shirt.